Question 1

Common bonds that drugs use to fit to their receptor sites include all of the following except:

Accepted Answer

A)  Ionic bonding.
B)  Van der Waals bonding.
C)  Hydrogen bonding.
D)  Compound bonding.E) A) and B)
F) A) and C)

Question 2

Which option is not one of the five parameters of pharmacokinetics?

Accepted Answer

A)  Absorption
B)  Distribution
C)  Tachyphylaxis
D)  MetabolismE) B) and C)
F) None of the above

Question 3

Which statement regarding an antagonist is true?

Accepted Answer

A)  Antagonists produce their effect by changing the receptor.
B)  Antagonists bind and block the effect of an endogenous agonist.
C)  Antagonists have an affinity for activating cell receptors.
D)  Antagonists induce the same response produced by the endogenous substance.E) None of the above
F) All of the above

Question 4

The thiazide diuretic hydrochlorothiazide is an example of a drug that acts on which type of receptor?

Accepted Answer

A)  Ion channel
B)  Nuclear receptors
C)  G-protein receptor complex
D)  Second messenger systemsE) B) and C)
F) A) and D)

Question 5

A prescriber is considering ordering a drug that has a high clearance rate,meaning that it is rapidly eliminated from the blood through the kidneys.Which statement is true regarding how the medication should be dosed?

Accepted Answer

A)  Lower doses are needed to keep the active compounds working.
B)  Higher doses are needed to keep the active compounds working.
C)  No dosing changes need to be made for this medication.
D)  Clearance rate has nothing to do with dosing medications.E) A) and B)
F) B) and D)

Question 6

The predominant organ of drug excretion is the:

Accepted Answer

A)  Liver.
B)  Small intestine.
C)  Skin.
D)  Kidney.E) A) and D)
F) B) and D)

Question 7

Drugs enter the bloodstream from the GI tract and then enter the liver via the hepatic portal vein before entering the general circulation.This route allows the liver to metabolize the drugs into less active or inactive metabolites/drugs before they are distributed throughout the body.This effect is known as the:

Accepted Answer

A)  Metabolic induction effect.
B)  Enzyme saturation effect.
C)  Steady state effect.
D)  First-pass effect.E) All of the above
F) A) and B)

Question 8

Drug distribution is not dependent on which of the following drug properties?

Accepted Answer

A)  Ability of a drug to permeate capillaries
B)  First-pass effect
C)  A drugs ability to bind to plasma proteins
D)  Fat- or water-soluble characteristicsE) A) and B)
F) C) and D)

Question 9

The pharmacologic term unbound or free drug refers to a drug that:

Accepted Answer

A)  Is not bound to its specific receptors.
B)  Is not bound to plasma proteins.
C)  Cannot exert a pharmacologic effect.
D)  Has been dissolved from its tablet state.E) C) and D)
F) A) and D)

Question 10

Which statement is true regarding renal excretion of drugs?

Accepted Answer

A)  Tubular secretion is the way in which most drugs are removed by the kidneys.
B)  Renal blood flow does not affect excretion of drugs.
C)  Large-molecular-weight drugs,such as heparin,are easily filtered by the glomeruli.
D)  Drugs that are tightly bound to plasma protein are readily filtered by the glomeruli.E) B) and D)
F) B) and C)

Question 11

Which statement regarding urinary pH is false?

Accepted Answer

A)  Urinary pH does not affect renal excretion of drugs.
B)  Urinary pH can be manipulated to facilitate drug excretion.
C)  In alkaline urine,acidic drugs are more readily ionized.
D)  Ionized substances are more soluble in water and thus they are easily excreted in urine.Chapter 2.An Introduction to Pharmacodynamics and PharmacokineticsE) A) and C)
F) B) and C)

Question 12

In the highly acidic pH of the stomach,which drugs would be best absorbed?

Accepted Answer

A)  Acidic drugs
B)  Neutral drugs
C)  Basic drugs
D)  pH has no affect on absorptionE) B) and D)
F) None of the above

Question 13

Which term describes the ability of a drug to reach the systemic circulation after an oral dosage?

Accepted Answer

A)  Extraction ratio
B)  First pass
C)  Bioavailability
D)  SolubilityE) A) and C)
F) None of the above

Question 14

The drug name "fluoxetine" is a:

Accepted Answer

A)  Chemical name.
B)  Generic name.
C)  Trade name.
D)  Brand name.E) C) and D)
F) A) and B)

Question 15

Some people are poor metabolizers of certain drugs.In the case of clopidogrel,which is activated by the liver,which statement about poor metabolizers is true?

Accepted Answer

A)  Poor metabolizers of clopidogrel do not efficiently convert it to its active form and thus may not receive its benefits.
B)  Poor metabolizers may not metabolize clopidogrel and may instead develop toxic effects at therapeutic dosages.
C)  The effects of clopidogrel are not changed in poor metabolizers.
D)  Poor metabolizers require lower doses of clopidogrel in order to avoid toxic effects.E) A) and B)
F) None of the above

Question 16

The drug name "Tylenol" is a:

Accepted Answer

A)  Chemical name.
B)  Generic name.
C)  Trade name.
D)  Clinical name.E) A) and D)
F) A) and B)

Question 17

Which of the following drugs is an antagonist?

Accepted Answer

A)  salmeterol (Serevent) 
B)  norepinephrine
C)  propanolol
D)  albuterol (Proventil) E) A) and B)
F) All of the above

Question 18

Which statement is true regarding factors that affect the absorption of drugs?

Accepted Answer

A)  pH has no affect on drug absorption.
B)  Increased blood flow to the gastrointestinal tract decreases absorption of orally administered drugs.
C)  The solubility of drugs affects their absorption.
D)  Absorption is not proportional to the surface area available.E) A) and B)
F) A) and C)

Exam 2: An Introduction to Pharmacodynamics and Pharmacokinetics

In the highly acidic pH of the stomach,which drugs would be best absorbed?

Correct Answer
verified

Which statement regarding urinary pH is false?

Correct Answer
verified

The drug name "Tylenol" is a:

Correct Answer
verified

Common bonds that drugs use to fit to their receptor sites include all of the following except:

Correct Answer
verified

Which term describes the ability of a drug to reach the systemic circulation after an oral dosage?

Correct Answer
verified

Which statement is true regarding renal excretion of drugs?

Correct Answer
verified

Some people are poor metabolizers of certain drugs.In the case of clopidogrel,which is activated by the liver,which statement about poor metabolizers is true?

Correct Answer
verified

Drug distribution is not dependent on which of the following drug properties?

Correct Answer
verified

Which of the following drugs is an antagonist?

Correct Answer
verified

The pharmacologic term unbound or free drug refers to a drug that:

Correct Answer
verified

The drug name "fluoxetine" is a:

Correct Answer
verified

The thiazide diuretic hydrochlorothiazide is an example of a drug that acts on which type of receptor?

Correct Answer
verified

Which statement is true regarding factors that affect the absorption of drugs?

Correct Answer
verified

Which option is not one of the five parameters of pharmacokinetics?

Correct Answer
verified

The predominant organ of drug excretion is the:

Correct Answer
verified

A prescriber is considering ordering a drug that has a high clearance rate,meaning that it is rapidly eliminated from the blood through the kidneys.Which statement is true regarding how the medication should be dosed?

Correct Answer
verified

Correct Answer
verified

Which statement regarding an antagonist is true?

Correct Answer
verified

Exam 2: An Introduction to Pharmacodynamics and Pharmacokinetics

In the highly acidic pH of the stomach,which drugs would be best absorbed?

Correct AnswerverifiedShow Answer

Which statement regarding urinary pH is false?

Correct AnswerverifiedShow Answer

The drug name "Tylenol" is a:

Correct AnswerverifiedShow Answer

Common bonds that drugs use to fit to their receptor sites include all of the following except:

Correct AnswerverifiedShow Answer

Which term describes the ability of a drug to reach the systemic circulation after an oral dosage?

Correct AnswerverifiedShow Answer

Which statement is true regarding renal excretion of drugs?

Correct AnswerverifiedShow Answer

Some people are poor metabolizers of certain drugs.In the case of clopidogrel,which is activated by the liver,which statement about poor metabolizers is true?

Correct AnswerverifiedShow Answer

Drug distribution is not dependent on which of the following drug properties?

Correct AnswerverifiedShow Answer

Which of the following drugs is an antagonist?

Correct AnswerverifiedShow Answer

The pharmacologic term unbound or free drug refers to a drug that:

Correct AnswerverifiedShow Answer

The drug name "fluoxetine" is a:

Correct AnswerverifiedShow Answer

The thiazide diuretic hydrochlorothiazide is an example of a drug that acts on which type of receptor?

Correct AnswerverifiedShow Answer

Which statement is true regarding factors that affect the absorption of drugs?

Correct AnswerverifiedShow Answer

Which option is not one of the five parameters of pharmacokinetics?

Correct AnswerverifiedShow Answer

The predominant organ of drug excretion is the:

Correct AnswerverifiedShow Answer

A prescriber is considering ordering a drug that has a high clearance rate,meaning that it is rapidly eliminated from the blood through the kidneys.Which statement is true regarding how the medication should be dosed?

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

Which statement regarding an antagonist is true?

Correct AnswerverifiedShow Answer

Correct Answer
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