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During DNA replication,_________are 1000- 2000 nucleotide long strands synthesized on the _________ strand to maintain the_________ of replication.


A) Okazaki fragments; leading,accuracy
B) primers,lagging; continuity
C) Okazaki fragments; lagging; bidirectionality
D) primers; leading; discontinuity
E) Okazaki fragments; leading; semidiscontinuity

F) A) and D)
G) C) and D)

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The discontinuous aspect of replication of DNA in vivo is caused by_________.


A) topoisomerases cutting the DNA in a random fashion
B) sister- chromatid exchanges
C) trinucleotide repeats
D) the 5' to 3' polarity restriction
E) polymerase slippage

F) C) and E)
G) A) and E)

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The protein responsible for the initial step in unwinding the DNA helix during replication of the bacterial chromosome is coded for by the_________ gene.


A) polB
B) dnaA
C) gyrA
D) polA
E) dnaE

F) B) and C)
G) A) and B)

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The protein product of the E.coli dnaE gene is a component of_________ .


A) DNA helicase
B) DNA ligase
C) primase
D) DNA polymerase III
E) DNA polymerase I

F) D) and E)
G) B) and C)

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The activity of_________ would be quickly undone in the absence of single- stranded binding protein.


A) DNA ligase
B) DNA polymerase I
C) primase
D) DNA polymerase III
E) DNA helicase

F) A) and C)
G) A) and E)

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Structures located at the ends of eukaryotic chromosomes are called_________ .


A) permissive mutations
B) recessive mutations
C) telomeres
D) centromeres
E) telomerases

F) A) and C)
G) A) and E)

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If DNA replication were fully conservative,how many intact parental double helices would have been detected in Meselson and Stahl's experiment after three rounds of replication?


A) 1
B) 7
C) 8
D) 0
E) 3

F) B) and C)
G) A) and E)

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Which of the following terms accurately describes the replication of DNA in vivo?


A) conservative
B) dispersive
C) nonreciprocal
D) semidiscontinuous
E) nonlinear

F) C) and D)
G) A) and D)

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Compare the rate of DNA replication in prokaryotes and eukaryotes.

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Eukaryotic DNA polymerases syn...

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What is meant by processivity of a DNA- synthesizing enzyme?

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The strength of the associatio...

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