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In which way would males and females differ in terms of chromosomes?


A) the total number of autosomes
B) the loci for the majority of their genes
C) the types of sex chromosomes
D) the inheritance of one X chromosome from their mother
E) the need for two sex chromosomes

F) C) and D)
G) B) and D)

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Which statement about Down syndrome is correct?


A) Down syndrome is caused by a third copy of chromosome 21.
B) Down syndrome is usually associated with chromosomal nondisjunction in meiosis.
C) Characteristics of Down syndrome include stubby fingers and a palm crease.
D) Individuals affected with Down syndrome display mental impairment.
E) All of the answer choices are correct about Down syndrome.

F) A) and B)
G) All of the above

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Genes that are linked do not show independent assortment.

A) True
B) False

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During meiosis, what process can sometimes "unlink" genes?


A) synapsis
B) crossing over
C) independent assortment
D) metaphase II
E) the formation of tetrads

F) B) and D)
G) C) and E)

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Which genetic disorder is the result of a deletion of a section of an individual's chromosome?


A) Williams syndrome
B) Klinefelter syndrome
C) Down syndrome
D) Turner syndrome
E) None of the answer choices is the result of a deletion of a section of an individual's chromosome.

F) A) and E)
G) C) and D)

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Hemophilia (h) is a sex-linked recessive trait. If a hemophiliac male marries a carrier female


A) 50% of their daughters will be hemophiliac.
B) 75% of their daughters will be hemophiliac.
C) 25% of their daughters will be hemophiliac.
D) 25% of their sons will be hemophiliac.
E) 75% of their sons will be hemophiliac.

F) A) and B)
G) None of the above

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A

Considering that males can have Klinefelter (XXY) syndrome, XYY, and normal XY chromosomal combinations, and females can have Turner (XO) syndrome, poly-X (XXX, XXXX) , and normal XX combinations, it is obvious that


A) male characteristics result from the presence of only one X chromosome.
B) male characteristics result from the absence of two or more X chromosomes.
C) male characteristics result from the minimal presence of one Y chromosome.
D) female characteristics result from the presence of two or more X chromosomes.
E) sex determination is a delicate balance between X and Y chromosomes.

F) B) and E)
G) A) and B)

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The location of a gene on a chromosome is called


A) a locus.
B) a lacunae.
C) a link.
D) a gene marker.

E) B) and C)
F) All of the above

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Which of the following sex-linked diseases is characterized by a waddling gait, toe walking, frequent falls, and difficulty in rising, and may appear as soon as the child starts to walk?


A) hemophilia
B) fragile X syndrome
C) color-blindness
D) Duchenne muscular dystrophy
E) None of the answer choices is true.

F) B) and E)
G) B) and C)

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Which refers to the loss of a complete chromosome?


A) inversion
B) translocation
C) deletion
D) duplication
E) monosomy

F) B) and C)
G) B) and E)

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Which of the following is a condition in which a person inherits an extra copy of a chromosome?


A) monosomy
B) disjunction
C) trisomy
D) inversion
E) duplication

F) C) and E)
G) A) and E)

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The chances of survival are greater when trisomy or monosomy involves the sex chromosomes.

A) True
B) False

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The most common autosomal abnormality seen among humans is


A) Edwards syndrome.
B) XXY.
C) Patau syndrome.
D) a deletion in chromosome 5.
E) trisomy 21.

F) B) and C)
G) C) and D)

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A female with two Barr bodies in her cells would have what combination of sex chromosomes?


A) XXY
B) XXXY
C) XXX
D) XX
E) XYY

F) None of the above
G) C) and D)

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C

If a woman is a carrier for the color-blind recessive allele and her husband has normal vision, what are their chances that a son will be color-blind?


A) none, because the father is normal
B) 50%, since the mother is only a carrier
C) 100%, because the mother has the gene
D) 25%, because the mother is a hybrid
E) None, since the son will also be just a carrier.

F) B) and E)
G) A) and E)

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An individual who has an XXY combination of sex chromosomes is said to have


A) Klinefelter syndrome.
B) Turner syndrome.
C) Down syndrome.
D) Fragile X syndrome.
E) cri du chat syndrome.

F) C) and D)
G) D) and E)

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Karyotyping can be used to diagnose which of the following genetic disorders?


A) Down syndrome
B) phenylketonuria
C) neurofibromatosis
D) cystic fibrosis
E) hemophilia

F) B) and D)
G) A) and E)

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A

Down syndrome


A) is due to disjunction of chromosomes.
B) individuals have two number 21 chromosomes.
C) may occur at a lower rate in women over 40.
D) can occur if the sperm has an extra copy of chromosome 21.
E) persons have normal-appearing eyelids.

F) B) and C)
G) B) and E)

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Which of the following conditions is due to a sex-linked gene?


A) color-blindness
B) hemophilia
C) muscular dystrophy
D) inability to see red or green
E) All of the answer choices are sex-linked conditions.

F) B) and D)
G) All of the above

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Which refers to the addition of a repeat segment of a chromosome?


A) inversion
B) translocation
C) deletion
D) duplication
E) monosomy

F) D) and E)
G) C) and D)

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