Question 1

What type of vaccine involves host synthesis of viral antigens?

Accepted Answer

A)   nucleic acid vaccine
B)   attenuated whole-agent vaccine
C)   conjugated vaccine
D)   toxoid vaccine
E)   subunit vaccineF) All of the above
G) A) and B)

Question 2

An ELISA for Hepatitis C has 95 percent sensitivity and 90 percent specificity. This means that the test

Accepted Answer

A)   detects 95 percent of the true positive samples and has 90 percent false positive results.
B)   detects 5 percent of the true positive samples and has 90 percent false positive results.
C)   detects 95 percent of the true positive samples and has 10 percent false positive results.
D)   detects 5 percent of the true positive samples and has 10 percent false positive results.
E)   detects 90 percent of the true positive samples and has 5 percent false positive results.F) A) and E)
G) A) and D)

Question 3

Agglutination tests use particulate antigens while precipitation tests use soluble antigens.

Accepted Answer

A) True 
 B)False

Question 4

Table 18.1
Antibody Titer
   Day 1  Day 7 Day 14  Day 21  Patient A 00256512 Patient B 1282565121024 Patient C 0000 Patient D 128128128128\begin{array} { | l | l | l | l | l | } \hline & 	ext { Day 1 } & 	ext { Day } 7 & 	ext { Day 14 } & 	ext { Day 21 } \\hline 	ext { Patient A } & 0 & 0 & 256 & 512 \\hline 	ext { Patient B } & 128 & 256 & 512 & 1024 \\hline 	ext { Patient C } & 0 & 0 & 0 & 0 \\hline 	ext { Patient D } & 128 & 128 & 128 & 128 \\hline\end{array} Patient A  Patient B  Patient C  Patient D ​ Day 1 01280128​ Day 702560128​ Day 14 2565120128​ Day 21 51210240128​​ 
-In Table 18.1, who probably has the disease?

Accepted Answer

A)   Patients A and C
B)   Patients A and D
C)   Patients B and C
D)   Patients C and D
E)   Patients A and B F) A) and B)
G) B) and E)

Question 5

A positive complement-fixation test is indicated by the lysis of the sheep red blood cells added in the indicator phase of the test.

Accepted Answer

A) True 
 B)False

Question 6

Western blotting uses antibodies to detect specific proteins in a mixture of proteins.

Accepted Answer

A) True 
 B)False

Question 7

Patientʹs serum, influenza virus, and red blood cells are mixed in a tube. What happens if the patient has antibodies against influenza virus?

Accepted Answer

A)   hemolysis
B)   agglutination
C)   hemagglutination
D)   complement fixation
E)   hemagglutination-inhibitionF) A) and E)
G) A) and C)

Question 8

Which of the following is a pregnancy test used to find the fetal hormone HCG in a womanʹs urine using anti-HCG and latex spheres?

Accepted Answer

A)   neutralization reaction
B)   immunofluorescence
C)   precipitation reaction
D)   direct agglutination reaction
E)   indirect agglutination reactionF) B) and E)
G) A) and D)

Question 9

The following steps are used to produce monoclonal antibodies. What is the fourth step?

Accepted Answer

A)   Culture the hybridoma in a selective medium.
B)   A B cell is activated to produce antibodies.
C)   Isolate antibody-producing B cells.
D)   Vaccinate a mouse.
E)   Fuse a B cell to a myeloma cell.F) B) and C)
G) A) and B)

Question 10

Blood typing tests are examples of hemagglutination reactions.

Accepted Answer

A) True 
 B)False

Question 11

Purified protein from Bordetella pertussis is used in a(n)

Accepted Answer

A)   nucleic acid vaccine.
B)   subunit vaccine.
C)   toxoid vaccine.
D)   attenuated whole-agent vaccine.
E)   conjugated vaccine.F) A) and C)
G) B) and E)

Question 12

Which of the following uses fluorescent-labeled antibodies?

Accepted Answer

A)   neutralization
B)   complement fixation
C)   precipitation
D)   flow cytometry
E)   agglutinationF) B) and E)
G) A) and B)

Question 13

A reaction between an antibody and soluble antigen-forming lattices is called a(n)

Accepted Answer

A)   agglutination reaction.
B)   complement fixation.
C)   immunofluorescence.
D)   neutralization reaction.
E)   precipitation reaction.F) None of the above
G) All of the above

Question 14

Inactivated tetanus toxin is a(n)

Accepted Answer

A)   nucleic acid vaccine.
B)   conjugated vaccine.
C)   subunit vaccine.
D)   toxoid vaccine.
E)   inactivated whole-agent vaccine.F) C) and E)
G) All of the above

Question 15

In an immunodiffusion test to diagnose the fungal disease histoplasmosis, a patientʹs serum is placed in a well in an agar plate. In a positive test, a precipitate forms as the serum diffuses from the well and meets material diffusing from a second well. In this test process, what is the most likely identity of the material in the second well?

Accepted Answer

A)   red blood cells
B)   a purified fungal antigen
C)   a purified protozoan antigen
D)   antibodies
E)   entire fungal cellsF) A) and D)
G) B) and E)

Question 16

Which item is from the patient in a direct ELISA test?

Accepted Answer

A)   antigen
B)   antibodies against the antigen
C)   antihuman immune serum
D)   substrate for the enzymeE) None of the above
F) B) and C)

Question 17

Which of the following is a test to determine the presence of soluble antigens in a patientʹs saliva?

Accepted Answer

A)   immunofluorescence
B)   precipitation reaction
C)   passive agglutination reaction
D)   neutralization reaction
E)   direct agglutination reactionF) A) and B)
G) All of the above

Question 18

Which of the following is NOT an advantage of live attenuated vaccine agents?

Accepted Answer

A)   They occasionally revert to virulent forms.
B)   They require few or no booster immunizations.
C)   The immune response generated by the vaccine closely mimics a real infection.
D)   They stimulate by cell-mediated and humoral immune responses.
E)   They elicit lifelong immunity.F) D) and E)
G) A) and D)

Question 19

In an agglutination test, eight serial dilutions to determine antibody titer were set up. Tube #1 contained a 1:2 dilution; tube #2, a 1:4, etc. If tube #6 is the last tube showing agglutination, what is the antibody titer?

Accepted Answer

A)   6
B)   1:6
C)   1:32
D)   32
E)   64F) A) and C)
G) A) and B)

Question 20

Figure 18.1
 
-Which component in Figure 18.1 came from the patient in this indirect ELISA test?

Accepted Answer

A)   a
B)   b
C)   c
D)   d
E)   eF) A) and B)
G) C) and D)

Exam 18: Practical Applications of Immunology

A positive complement-fixation test is indicated by the lysis of the sheep red blood cells added in the indicator phase of the test.

Correct Answer
verified

Patientʹs serum, influenza virus, and red blood cells are mixed in a tube. What happens if the patient has antibodies against influenza virus?

Correct Answer
verified

Correct Answer
verified

Western blotting uses antibodies to detect specific proteins in a mixture of proteins.

Correct Answer
verified

Inactivated tetanus toxin is a(n)

Correct Answer
verified

Which of the following is a pregnancy test used to find the fetal hormone HCG in a womanʹs urine using anti-HCG and latex spheres?

Correct Answer
verified

The following steps are used to produce monoclonal antibodies. What is the fourth step?

Correct Answer
verified

Which of the following is a test to determine the presence of soluble antigens in a patientʹs saliva?

Correct Answer
verified

Correct Answer
verified

A reaction between an antibody and soluble antigen-forming lattices is called a(n)

Correct Answer
verified

Blood typing tests are examples of hemagglutination reactions.

Correct Answer
verified

Which of the following is NOT an advantage of live attenuated vaccine agents?

Correct Answer
verified

In an agglutination test, eight serial dilutions to determine antibody titer were set up. Tube #1 contained a 1:2 dilution; tube #2, a 1:4, etc. If tube #6 is the last tube showing agglutination, what is the antibody titer?

Correct Answer
verified

Figure 18.1 -Which component in Figure 18.1 came from the patient in this indirect ELISA test?

Correct Answer
verified

Which of the following uses fluorescent-labeled antibodies?

Correct Answer
verified

Which item is from the patient in a direct ELISA test?

Correct Answer
verified

What type of vaccine involves host synthesis of viral antigens?

Correct Answer
verified

Agglutination tests use particulate antigens while precipitation tests use soluble antigens.

Correct Answer
verified

An ELISA for Hepatitis C has 95 percent sensitivity and 90 percent specificity. This means that the test

Correct Answer
verified

Purified protein from Bordetella pertussis is used in a(n)

Correct Answer
verified

Exam 18: Practical Applications of Immunology

A positive complement-fixation test is indicated by the lysis of the sheep red blood cells added in the indicator phase of the test.

Correct AnswerverifiedShow Answer

Patientʹs serum, influenza virus, and red blood cells are mixed in a tube. What happens if the patient has antibodies against influenza virus?

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

Western blotting uses antibodies to detect specific proteins in a mixture of proteins.

Correct AnswerverifiedShow Answer

Inactivated tetanus toxin is a(n)

Correct AnswerverifiedShow Answer

Which of the following is a pregnancy test used to find the fetal hormone HCG in a womanʹs urine using anti-HCG and latex spheres?

Correct AnswerverifiedShow Answer

The following steps are used to produce monoclonal antibodies. What is the fourth step?

Correct AnswerverifiedShow Answer

Which of the following is a test to determine the presence of soluble antigens in a patientʹs saliva?

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

A reaction between an antibody and soluble antigen-forming lattices is called a(n)

Correct AnswerverifiedShow Answer

Blood typing tests are examples of hemagglutination reactions.

Correct AnswerverifiedShow Answer

Which of the following is NOT an advantage of live attenuated vaccine agents?

Correct AnswerverifiedShow Answer

In an agglutination test, eight serial dilutions to determine antibody titer were set up. Tube #1 contained a 1:2 dilution; tube #2, a 1:4, etc. If tube #6 is the last tube showing agglutination, what is the antibody titer?

Correct AnswerverifiedShow Answer

Figure 18.1 -Which component in Figure 18.1 came from the patient in this indirect ELISA test?

Correct AnswerverifiedShow Answer

Which of the following uses fluorescent-labeled antibodies?

Correct AnswerverifiedShow Answer

Which item is from the patient in a direct ELISA test?

Correct AnswerverifiedShow Answer

What type of vaccine involves host synthesis of viral antigens?

Correct AnswerverifiedShow Answer

Agglutination tests use particulate antigens while precipitation tests use soluble antigens.

Correct AnswerverifiedShow Answer

An ELISA for Hepatitis C has 95 percent sensitivity and 90 percent specificity. This means that the test

Correct AnswerverifiedShow Answer

Purified protein from Bordetella pertussis is used in a(n)

Correct AnswerverifiedShow Answer

Correct Answer
verified

Correct Answer
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Correct Answer
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Correct Answer
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