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A patient who has been taking isoniazid (Isotamine) has a new prescription for pyridoxine (vitamin B₆) .She asks the nurse why she needs this medication.The nurse explains that pyridoxine is given concurrently with the isoniazid to prevent which of the following?


A) Hair loss
B) Renal failure
C) Neurological adverse effects
D) Heart failure

E) A) and C)
F) None of the above

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C

A patient has been prescribed an antituberculosis therapy.Which important points should the nurse emphasize when teaching the patient about this therapy? Select all that apply.


A) Take the medications until the symptoms disappear.
B) Take the medications at the same time every day.
C) You are considered contagious for most of the illness and must take precautions to prevent spreading the disease.
D) The medications may be stopped if you have severe adverse effects.
E) Alcoholic beverages should be avoided while on this therapy.
F) If you notice reddish-brown or reddish-orange urine,stop the drug and contact your doctor right away.
G) If you experience a burning or tingling in your fingers or toes,report this to your physician immediately.
H) Oral contraceptives may not work while on these drugs,so you will need to use another form of birth control.

I) B) and C)
J) E) and H)

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Women taking oral contraceptives need to be concerned when beginning rifampin (Rifadin) therapy because of which of the following?


A) The increased risk of thrombophlebitis
B) A higher dose of rifampin will be necessary.
C) Oral contraceptives are ineffective while the patient is taking rifampin.
D) The incidence of adverse effects is greater when the two drugs are taken together.

E) B) and C)
F) A) and C)

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Family members exposed to a patient with active tuberculosis (TB) may require prophylactic drug therapy.How long do they need to take this therapy?


A) 6 months
B) 12 months
C) 18 months
D) 24 months

E) A) and B)
F) None of the above

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Which antituberculosis drug may cause a decrease in visual acuity resulting from optic neuritis?


A) rifampin (Rifadin)
B) isoniazid (Isotamine)
C) ethambutol (Etibi)
D) streptomycin

E) A) and B)
F) A) and C)

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Which of the following indicates a patient's therapeutic response to antituberculosis drugs?


A) A cessation of the chronic cough
B) Two consecutive negative purified protein derivative (PPD) tuberculin skin test results over 2 months
C) An increased tolerance to the medication therapy and fewer reports of adverse effects
D) A decrease in symptoms of tuberculosis (TB) and improved chest X-rays and sputum cultures

E) All of the above
F) C) and D)

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When assessing patients who are to receive antituberculosis therapy,the nurse should monitor for signs of which of the following?


A) Glaucoma
B) Weight gain
C) Heart failure
D) Hepatic impairment

E) A) and D)
F) B) and D)

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D

Which of the following has a significant drug interaction with isoniazid (Isotamine) ?


A) Alcohol
B) Nicotine
C) Antacids
D) Laxatives

E) B) and C)
F) None of the above

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C

A patient has started drug therapy for tuberculosis and asks the nurse how long he will be on the medications.Which of the following statements is the nurse's best response to the patient?


A) Drug therapy will last until the symptoms have stopped.
B) Drug therapy will continue until the tuberculosis develops resistance.
C) He should expect to take these drugs for up to 24 months.
D) He will be on tuberculosis drug therapy for the rest of his life.

E) B) and C)
F) All of the above

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Patients taking isoniazid (Isotamine) should watch for and report which of the following potential adverse effects?


A) Rash
B) Headache and nervousness
C) Insomnia
D) Numbness and tingling of extremities

E) B) and C)
F) B) and D)

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Which of the following is the reason for using multidrug therapy in the treatment of tuberculosis (TB) ?


A) Multiple drugs are required to eradicate the TB.
B) The use of multiple medications reduces the chance of the TB becoming drug resistant.
C) Multidrug therapy will have a faster effect than single-drug therapy.
D) Using multidrug therapy enhances the effect of each drug.

E) A) and B)
F) B) and C)

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