Question 1

Which one of the following is involved in the breakdown of glycogen?

Accepted Answer

A)   inorganic phosphate
B)   ATP
C)   branching enzyme
D)   hexokinaseE) A) and B)
F) None of the above

Question 2

Cori disease arises from a deficient debranching enzyme.Describe the consequences for glycogen metabolism.

Accepted Answer

Individuals with Cori disease ...

Question 3

Draw a glucose molecule and indicate which atom is linked to glycogen during the glycogen synthesis process.

Accepted Answer

The C1 of the incomi...

Question 4

The opposing glycolysis and gluconeogenesis enzymes hexokinase and glucose-6-phosphatase are located with which cellular locations,respectively?

Accepted Answer

Hexokinase is found in the cyt...

Question 5

List the three enzymes in glycolysis that are bypassed in gluconeogenesis and match them with the enzymes in gluconeogenesis that replace them.

Accepted Answer

(1)Hexokinase is replaced by glucose-1-p...

Question 6

How many of the 10 glycolysis reactions use the same enzyme in the gluconeogenesis pathway?

Accepted Answer

A)   10
B)   7
C)   5
D)   3E) A) and D)
F) B) and D)

Question 7

Which of the following molecules might inhibit the regulated enzymes in glycolysis?

Accepted Answer

A)   NAD+
B)   ATP
C)   AMP
D)   fructose-2,6-bisphosphateE) None of the above
F) A) and B)

Question 8

What is the name of the enzyme that removes phosphate groups from the regulated glycogen metabolism enzymes to reverse their activity?

Accepted Answer

A)   phosphorylase kinase
B)   protein phosphatase 1
C)   insulin
D)   protein kinase AE) C) and D)
F) None of the above

Question 9

The branching enzyme

Accepted Answer

A)   
B)   
C)   
D)   E) All of the above
F) A) and B)

Question 10

Which of the following molecules would activate phosphofructokinase 1 (PFK1) ?

Accepted Answer

A)   NADH
B)   AMP
C)   ATP
D)   pyruvateE) A) and B)
F) A) and C)

Question 11

Which correctly describes the role of the transport system shown below?

Accepted Answer

A)   It provides an alternate fate for pyruvate degradation.
B)   It provides a source of NADH for gluconeogenesis via malate transport.
C)   It converts NADH equivalents into reduced forms of carbon.
D)   It allows for pyruvate transport into and out of the mitochondria.E) None of the above
F) All of the above

Question 12

The pentose phosphate pathway

Accepted Answer

A)   resembles the TCA cycle in that it couples the loss of CO2 with the formation of NADH.
B)   allows 5C sugars to converge with or diverge from the glycolysis pathway.
C)   contains 2C, 3C, 4C, 5C, 6C, and 7C sugar molecules.
D)   enables the production of ATP from glucose.E) A) and D)
F) B) and C)

Question 13

The main function of the pentose phosphate pathway is to provide

Accepted Answer

A)   the cell with backup capability when glycolysis is inhibited.
B)   energy and reducing power.
C)   a mechanism for the utilization of the carbon skeletons of excess amino acids.
D)   a source of ribose and NADPH.E) A) and B)
F) B) and D)

Question 14

Which enzyme class catalyzes the following pentose phosphate pathway reaction (note that there may be some missing reactants and products) ?

Accepted Answer

A)   lyase
B)   isomerase
C)   transferase
D)   oxidoreductaseE) A) and B)
F) None of the above

Question 15

The hormone insulin stimulates __________ and inhibits __________,leading to a(n) __________ in the glucose levels.

Accepted Answer

A)   glycogen synthase; glycogen phosphorylase; decrease
B)   glycogen phosphorylase; glycogen synthase; decrease
C)   glycogen synthase; glycogen phosphorylase; increase
D)   glycogen phosphorylase; glycogen synthase; increaseE) B) and D)
F) B) and C)

Question 16

What triggers the Cori cycle?

Accepted Answer

A)   a buildup of cellular NAD+
B)   oxygen-limited working muscle cells
C)   low levels of glucose in the muscle cells
D)   elevated glucagon levelsE) All of the above
F) B) and C)

Question 17

What are the three main sources of carbon in animals making glucose with the gluconeogenesis pathway?

Accepted Answer

(1)Glycerol from fats,(2)lacta...

Question 18

What class of enzymes in the oxidative phase of the pentose phosphate pathway is responsible for the production of NADPH?

Accepted Answer

Dehydrogen...

Question 19

If the ratio of NADP+ to NADPH were high,the

Accepted Answer

A)   net production of ATP would occur.
B)   pentose phosphate pathway oxidative phase would be activated.
C)   cellular levels of nucleotides would have to increase from an activated pentose phosphate pathway.
D)   pentose phosphate pathway would be inhibited.E) All of the above
F) None of the above

Question 20

What molecule activates the pentose phosphate pathway?

Accepted Answer

A)   NADP+
B)   ribulose-5-phosphate
C)   ADP
D)   NADHE) A) and B)
F) B) and D)

Exam 14: Carbohydrate Metabolism

Cori disease arises from a deficient debranching enzyme.Describe the consequences for glycogen metabolism.

Correct AnswerverifiedIndividuals with Cori disease ...View AnswerShow Answer

The hormone insulin stimulates __________ and inhibits __________,leading to a(n) __________ in the glucose levels.

Correct AnswerverifiedShow Answer

List the three enzymes in glycolysis that are bypassed in gluconeogenesis and match them with the enzymes in gluconeogenesis that replace them.

Correct Answerverified(1)Hexokinase is replaced by glucose-1-p...View AnswerShow Answer

What triggers the Cori cycle?

Correct AnswerverifiedShow Answer

Which enzyme class catalyzes the following pentose phosphate pathway reaction (note that there may be some missing reactants and products) ?

Correct AnswerverifiedShow Answer

Draw a glucose molecule and indicate which atom is linked to glycogen during the glycogen synthesis process.

Correct AnswerverifiedThe C1 of the incomi...View AnswerShow Answer

The opposing glycolysis and gluconeogenesis enzymes hexokinase and glucose-6-phosphatase are located with which cellular locations,respectively?

Correct AnswerverifiedHexokinase is found in the cyt...View AnswerShow Answer

Which of the following molecules would activate phosphofructokinase 1 (PFK1) ?

Correct AnswerverifiedShow Answer

If the ratio of NADP+ to NADPH were high,the

Correct AnswerverifiedShow Answer

What is the name of the enzyme that removes phosphate groups from the regulated glycogen metabolism enzymes to reverse their activity?

Correct AnswerverifiedShow Answer

How many of the 10 glycolysis reactions use the same enzyme in the gluconeogenesis pathway?

Correct AnswerverifiedShow Answer

The branching enzyme

Correct AnswerverifiedShow Answer

What are the three main sources of carbon in animals making glucose with the gluconeogenesis pathway?

Correct Answerverified(1)Glycerol from fats,(2)lacta...View AnswerShow Answer

Which correctly describes the role of the transport system shown below?

Correct AnswerverifiedShow Answer

What molecule activates the pentose phosphate pathway?

Correct AnswerverifiedShow Answer

The main function of the pentose phosphate pathway is to provide

Correct AnswerverifiedShow Answer

The pentose phosphate pathway

Correct AnswerverifiedShow Answer

What class of enzymes in the oxidative phase of the pentose phosphate pathway is responsible for the production of NADPH?

Correct AnswerverifiedDehydrogen...View AnswerShow Answer

Which of the following molecules might inhibit the regulated enzymes in glycolysis?

Correct AnswerverifiedShow Answer

Which one of the following is involved in the breakdown of glycogen?

Correct AnswerverifiedShow Answer

Correct Answer
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Individuals with Cori disease ...
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The hormone insulin stimulates and inhibits ,leading to a(n) __ in the glucose levels.

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Correct Answer
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(1)Hexokinase is replaced by glucose-1-p...
View Answer

Correct Answer
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Correct Answer
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Correct Answer
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The C1 of the incomi...
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Hexokinase is found in the cyt...
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If the ratio of NADP⁺ to NADPH were high,the

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Correct Answer
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Correct Answer
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Correct Answer
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(1)Glycerol from fats,(2)lacta...
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Correct Answer
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Correct Answer
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Dehydrogen...
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Correct Answer
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