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A patient who has been taking isoniazid (Isotamine) has a new prescription for pyridoxine (vitamin B6) and asks the nurse why this medication is needed.The nurse explains that pyridoxine is given concurrently with the isoniazid to prevent which condition?


A) Hair loss
B) Renal failure
C) Neurological adverse effects
D) Heart failure

E) B) and D)
F) None of the above

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Which antitubercular drug may cause retrobulbar neuritis?


A) rifampin (Rifadin)
B) isoniazid (Isotamine)
C) ethambutol (Etibi)
D) streptomycin

E) A) and C)
F) B) and D)

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Which has a significant drug interaction with isoniazid (Isotamine) ?


A) Alcohol
B) Nicotine
C) Antacids
D) Laxatives

E) A) and C)
F) A) and D)

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Patients taking isoniazid (Isotamine) should watch for and report which potential adverse effect(s) ?


A) Rash
B) Headache and nervousness
C) Insomnia
D) Numbness and tingling of extremities

E) A) and B)
F) C) and D)

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D

When assessing patients who are to receive antitubercular therapy,the nurse should monitor for which sign?


A) Glaucoma
B) Weight gain
C) Heart failure
D) Hepatic impairment

E) A) and C)
F) A) and B)

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A patient has been prescribed an anti-TB therapy.What should the nurse say about this medication to the patient? (Select all that apply.)


A) "Take the medications until the symptoms disappear."
B) "Take the medications at the same time every day."
C) "You are considered contagious for most of the illness and must take precautions to prevent spreading the disease."
D) "The medications may be stopped if you have severe adverse effects."
E) "Alcoholic beverages should be avoided while on this therapy."
F) "If you notice reddish-brown or reddish-orange urine, stop the drug and contact your doctor right away."
G) "If you experience a burning or tingling in your fingers or toes, report this to your physician immediately."
H) "Oral contraceptives may not work while on these drugs, so you will need to use another form of birth control."

I) D) and H)
J) C) and D)

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What indicates a patient's therapeutic response to antitubercular drugs?


A) Cessation of the chronic cough
B) Two consecutive negative purified protein derivative tuberculin skin test results over 2 months
C) An increased tolerance to the medication therapy and fewer reports of adverse effects
D) A decrease in symptoms of tuberculosis (TB) and improved chest X-rays and sputum cultures

E) A) and D)
F) A) and C)

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What information is the nurse to provide to a woman who is beginning rifampin therapy and is currently taking an oral contraceptive?


A) There is an increased risk of thrombophlebitis.
B) A higher dose of rifampin will be necessary.
C) Oral contraceptives are ineffective while the patient is taking rifampin.
D) The incidence of adverse effects is greater when the two drugs are taken together.

E) All of the above
F) B) and D)

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C

Family members exposed to a patient with active TB may require prophylactic drug therapy.How long do they need to take this therapy?


A) 6 months
B) 9 months
C) 18 months
D) 24 months

E) A) and D)
F) A) and B)

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B

Which is the reason for using multidrug therapy in the treatment of TB?


A) Multiple drugs are required to eradicate TB.
B) The use of multiple medications reduces the chance of TB becoming drug resistant.
C) Multidrug therapy will have a faster effect than will single-drug therapy.
D) Using multidrug therapy enhances the effect of each drug.

E) B) and C)
F) None of the above

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A patient who has started drug therapy for TB asks the nurse how long the medications will have to be taken.Which statement is the nurse's best response to the patient's question?


A) Drug therapy will last until the symptoms have stopped.
B) Drug therapy will continue until the TB develops resistance.
C) The patient should expect to take these drugs for up to 24 months.
D) The tuberculosis drug therapy will continue for the rest of the patient's life.

E) A) and B)
F) A) and C)

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