Question 1

Use the following to answer questions:
The diagram below shows how DNA is sequenced. 
-At which step are the DNA segments first separated by length?

Accepted Answer

A)   Step 2
B)   Step 3
C)   Step 4
D)   Step 5
E)   Step 6 or laterF) A) and D)
G) B) and D)

Question 2

Which of the following fields or approaches is most likely to lead directly to a reduction in the negative side effects associated with a drug used to treat diabetes?

Accepted Answer

A)   Comparative genomics
B)   Metagenomics
C)   Metabolomics
D)   Pharmacogenomics
E)   Selective inactivationF) A) and D)
G) C) and E)

Question 3

Which of the following statements about the benefits of knowing genomic sequences is false?

Accepted Answer

A)   Open reading frames for proteins may be identified.
B)   RNA genes may be identified.
C)   The sequence of a gene for a protein always allows the determination of the protein's function.
D)   Evolutionary relationships among organisms may be traced.
E)   Noncoding sequences may be analyzed.F) B) and E)
G) B) and C)

Question 4

Transposons differ from transposable elements in that

Accepted Answer

A)   transposons may carry additional genes.
B)   transposons are smaller than transposable elements.
C)   transposons cannot disrupt genes.
D)   transposable elements often contain genes for antibiotic resistance.
E)   None of the aboveF) A) and C)
G) B) and C)

Question 5

Use the following to answer questions

The diagram below shows the use of transposons as mutagens.
 
-Based on the diagram, which of the following is true?

Accepted Answer

A)   Gene A is essential because there was growth when gene A was mutagenized.
B)   Gene A is not essential because there was growth when gene A was mutagenized.
C)   Gene A is not essential because there was no growth when gene A was mutagenized
D)   Gene A is essential because there was no growth when gene A was mutagenized.
E)   Whether gene A is essential or not depends on gene B.F) B) and E)
G) None of the above

Question 6

Which of the following was not one of the discoveries that resulted from the genome sequencing of plants?

Accepted Answer

A)   There are more protein-coding genes in animals than plants.
B)   Many Arabidopsis genes are duplicated due to chromosomal rearrangements.
C)   There are more genes in plants that are similar to each other than there are genes that are unique.
D)   Plants have many genes whose products are used for defense against microbes and herbivores.
E)   All of the above are true.F) A) and C)
G) B) and D)

Question 7

The transposable element bandit, which was discovered in the dog hookworm, appears able to move to the hookworm's mammalian hosts. Because it does not use an RNA intermediate, the bandit element has been classified as a(n) _______.

Accepted Answer

The answer of The transposable element bandit, which was discovered...

Question 8

Analyzing the human genome has revealed many genes that cause disease when mutated. Why have we not been able to eliminate those diseases now that we know the genes that are involved?

Accepted Answer

We have not been able to eliminate genet...

Question 9

A lab sequencing the DNA of various species of pathogenic bacteria with the goal of determining their evolutionary relationships would be practicing _______ genomics.

Accepted Answer

A)   functional
B)   operational
C)   meta-
D)   comparative
E)   eukaryoticF) All of the above
G) A) and D)

Question 10

Genomics has revealed that the bacterium that causes tuberculosis has more 250 genes that metabolize lipids. What does this finding suggest about the bacterium and about medicinal approaches to this disease?

Accepted Answer

The tuberculosis bacterium mus...

Question 11

The bacterium responsible for the most common sexually transmitted disease in the United States is

Accepted Answer

A)   Streptomyces coelicolor.
B)   Rickettsia prowazekii.
C)   Chlamydia trachomatis.
D)   Treponema pallidum.
E)   Neisseria gonorrhoeae.F) C) and D)
G) B) and D)

Question 12

In the context of metabolomics, glucose would be considered a

Accepted Answer

A)   haplotype.
B)   primary metabolite.
C)   secondary metabolite.
D)   tertiary metabolite.
E)   None of the aboveF) B) and C)
G) C) and D)

Question 13

What is the most likely explanation for the abundance of transposons in eukaryotic genomes?

Accepted Answer

A)   They are needed to provide mutations.
B)   They are needed to increase genetic recombination.
C)   They are genomic parasites.
D)   They assist in the process of DNA repair.
E)   They provide reverse transcriptase.F) All of the above
G) A) and D)

Question 14

Which of the following statements about the human genome is false?

Accepted Answer

A)   Most human genes have introns.
B)   Genes are evenly distributed among the chromosomes.
C)   Only about 2 percent of the genome codes for proteins.
D)   Transposons are common.
E)   The "average" human gene codes for more than just one protein.F) A) and E)
G) A) and C)

Question 15

Which one of the following does not represent information that we have gained from genome sequencing?

Accepted Answer

A)   Mycobacteria have many genes devoted to metabolizing fats.
B)   There is extensive genetic exchange between different kinds of bacteria.
C)   Genomes can be sequenced even when organisms cannot be cultured.
D)   Much of the eukaryotic genome contains coding sequences.
E)   The majority of genes in C. elegans are cell signaling genes.F) C) and E)
G) D) and E)

Question 16

Comparisons of yeast and bacterial cell genomes have revealed that

Accepted Answer

A)   yeast cells have more genes devoted to the basic functions of survival than bacteria do.
B)   eukaryotic cells are structurally similar to bacterial cells in terms of complexity.
C)   there are more genes for targeting proteins to organelles in yeast than in bacteria.
D)   the histones of bacteria are very similar to those of yeast.
E)   bacteria and yeast are both haploid.F) A) and D)
G) C) and D)

Question 17

The incorporation of a _______ will terminate the synthesis of DNA. This principle is used in conventional methods of DNA sequencing.

Accepted Answer

The answer of The incorporation of a _______ will terminate...

Question 18

Transposons

Accepted Answer

A)   always use RNA for replication.
B)   are approximately 50 bp long.
C)   are made up of either DNA or RNA.
D)   do not contain genes coding for proteins.
E)   make up about 40 percent of the human genome.F) A) and D)
G) B) and D)

Question 19

Techniques associated with which of the following are most likely to generate ethical concerns?

Accepted Answer

A)   Metagenomics
B)   Creation of a minimal genome
C)   Shotgun sequencing
D)   Hierarchical sequencing
E)   Comparative genomicsF) C) and D)
G) D) and E)

Question 20

Which is not true of metagenomics?

Accepted Answer

A)   It has been done with bacteria.
B)   It is done on rRNA sequences.
C)   It has revealed many new metabolic capacities.
D)   It involves extracting DNA from the environment.
E)   It cannot be done on seawater.F) B) and C)
G) C) and E)

Exam 17: Genomes

Use the following to answer questions: The diagram below shows how DNA is sequenced. -At which step are the DNA segments first separated by length?

Correct AnswerverifiedShow Answer

Which of the following fields or approaches is most likely to lead directly to a reduction in the negative side effects associated with a drug used to treat diabetes?

Correct AnswerverifiedShow Answer

What is the most likely explanation for the abundance of transposons in eukaryotic genomes?

Correct AnswerverifiedShow Answer

Analyzing the human genome has revealed many genes that cause disease when mutated. Why have we not been able to eliminate those diseases now that we know the genes that are involved?

Correct AnswerverifiedWe have not been able to eliminate genet...View AnswerShow Answer

The incorporation of a _______ will terminate the synthesis of DNA. This principle is used in conventional methods of DNA sequencing.

Correct AnswerverifiedShow Answer

The transposable element bandit, which was discovered in the dog hookworm, appears able to move to the hookworm's mammalian hosts. Because it does not use an RNA intermediate, the bandit element has been classified as a(n) _______.

Correct AnswerverifiedShow Answer

Use the following to answer questions The diagram below shows the use of transposons as mutagens. -Based on the diagram, which of the following is true?

Correct AnswerverifiedShow Answer

Transposons

Correct AnswerverifiedShow Answer

In the context of metabolomics, glucose would be considered a

Correct AnswerverifiedShow Answer

Which one of the following does not represent information that we have gained from genome sequencing?

Correct AnswerverifiedShow Answer

The bacterium responsible for the most common sexually transmitted disease in the United States is

Correct AnswerverifiedShow Answer

Which of the following statements about the benefits of knowing genomic sequences is false?

Correct AnswerverifiedShow Answer

A lab sequencing the DNA of various species of pathogenic bacteria with the goal of determining their evolutionary relationships would be practicing _______ genomics.

Correct AnswerverifiedShow Answer

Genomics has revealed that the bacterium that causes tuberculosis has more 250 genes that metabolize lipids. What does this finding suggest about the bacterium and about medicinal approaches to this disease?

Correct AnswerverifiedThe tuberculosis bacterium mus...View AnswerShow Answer

Which of the following was not one of the discoveries that resulted from the genome sequencing of plants?

Correct AnswerverifiedShow Answer

Comparisons of yeast and bacterial cell genomes have revealed that

Correct AnswerverifiedShow Answer

Which is not true of metagenomics?

Correct AnswerverifiedShow Answer

Transposons differ from transposable elements in that

Correct AnswerverifiedShow Answer

Techniques associated with which of the following are most likely to generate ethical concerns?

Correct AnswerverifiedShow Answer

Which of the following statements about the human genome is false?

Correct AnswerverifiedShow Answer

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We have not been able to eliminate genet...
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The tuberculosis bacterium mus...
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